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In the swine flu vaccine has been developed, the technology of the most mature and are mainly used in the production H1NI type and price or bivalent H3N2 subtype swine influenza inactivated whole-virus vaccine. Mostly in the form of oil-adjuvant vaccine, inactivated agents commonly used formaldehyde or BEI. It was reported that swine influenza inactivated vaccine can effectively protect weaned piglets and pigs against SI, so that the incidence was reduced by 30% to 70% so that the deaths fall by 60% ~ 87%. At present, such vaccines have achieved a number of countries in Europe and the United States commercial providers, such as the Intervet's End-FLUence (with Imugen) and the End FLUence (with Microsol Diluvac Forte), Pfizer Inc. FluSure, and Schering Plough Animal Health Corporation MaxiVac-FIu, MaxiVac Excell 3 and so on. China South China Agricultural University, Harbin Veterinary Research Institute, and other units are also swine influenza oil-emulsion inactivated vaccine development has done a lot of work, its research results show that the cultivated strains isolated from China after the preparation of the H1 subtype; 91H3 subtypes unit and bivalent swine influenza oil-emulsion inactivated vaccine after the first 3 weeks after immunization Hl antibody titer 1:160 can be achieved for more than 4 weeks after vaccination HI antibody levels of more than 1:400, to 12NHI antibody titers after immunization can still maintain 1:100 or more, more than 1:80 of antibody-positive criteria. If you make two free, then the higher levels of HI antibody, effective period of protection can be achieved more than 6 months, fully able to meet the immunization needs of a variety of day-old pigs. Currently, these vaccines have been through clinical testing, is to declare a new veterinary certificate, I believe that in the near future can be made for commercialization of the vaccine on the market.
Swine influenza inactivated whole-virus vaccine, while having safe, efficient, low production costs, long duration of effective antibodies, etc., but there are also slower to produce antibodies and induce cellular immune capacity of weak and strong enough stress response. In particular kinds of drugs, mostly from the vaccine strain in the epidemic, once the vaccine, the virus occurred during the leak, likely to cause environmental pollution, trigger a new outbreak. To this end, scientists have also been exploring the development of new swine flu vaccine.

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