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H is known as red blood cell agglutinin, N is called neuraminidase, which are glycoproteins located in the virus surface. H are 1-15 subtypes, N there are 1-9 subtypes (in the case of influenza A virus). Due to a combination of H and N are different toxicity and spread the virus is not the same.
1918 ~ 1920, a pandemic of this epidemic first appeared in the eastern United States in January 1918, in April 1918 are popular in the French Army, after the rapid spread of global consequences. The pandemic is known as the greatest plague in human history, resulting in the total number of deaths estimated to be about 50 million people. With regard to the pandemic pathogen, according to serological traceability that is a swine Hsw1N1 (H1N1) influenza virus.
April 25, 2009, suddenly came the outbreak of swine flu situation in Mexico.
U.S. government officials, April 28, said they are considering for the moment raging flu epidemic for the name, because "swine flu" misleading, this misconception that in Mexico, the United States and other countries with disease outbreaks related to consumption of pork.
The Associated Press reported that the virus is actually a mixture of concentrated swine influenza virus, human influenza viruses and avian influenza virus characteristics. As U.S. officials believe that, although the swine influenza virus in which to play a certain role, but the emergence of influenza now simply named "swine flu" is not accurate, but the North American pork and pork products for export with a serious impact.
U.S. Centers for Disease Control and Prevention said that eating pork will not be infected with swine influenza, the virus could now spread from person to person.
U.S. Centers for Disease Control and Prevention announced that swine flu was renamed to "Influenza A H1N1 flu," because the virus is not spread by pigs.
Swine influenza virus (Swine influenza virus, SIV) is a kind of pigs can cause local Influenza Orthomyxoviridae (Orthomyxoviruses). Currently in the laboratory of the isolated virus was identified as a C-type multi-influenza virus, or influenza A virus, one of the sub-species. Under the electron microscope A-type influenza virus, swine influenza there are many different varieties, namely: H1N1, H1N2, H3N1, H3N2, and H2N3 subtypes of influenza A virus can lead to swine influenza infection.
Now in Mexico, an outbreak of swine influenza type A influenza virus from pigs caused by respiratory diseases, preliminary study to detect the virus is influenza A virus, carrying the H1N1 subtype swine influenza virus strains, including avian flu, swine three kinds of influenza and human influenza genes of influenza virus DNA fragments have both Asian and African swine flu swine influenza virus signatures.
Reuters news agency quoted the U.S. research scientists report that this new type of influenza virus to swine flu, because scientists have detected in the patient's body H1N1 subtype swine influenza virus strains, but this new type of influenza virus has a virus hybrid characteristics.
World Health Organization said that the trigger Influenza H1N1 influenza virus is avian and human influenza after "shuffling" effect generated by new virus. After the exchange of the virus encounters a different gene mutation for a new type of mixed types of viruses, so their lack of human immunity. This will enable the swine flu epidemic affected the scope and follow-up impact is difficult to estimate. However, the virus attacks nature of individual differences in human immunity and human influenza from a confrontation in a variety of acquired resistance are the determining the integrated status of the decisive factors in this epidemic.
According to the U.S. record of human infection with H1N1 swine influenza virus outbreak in 1976 and 1988 occurred, resulting in two deaths.

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